Spondylosis means break in connection between two vertebral body. It causes back pain and sciatica due to nerve irritation. It usually happens due to congenital defect or athletics or trauma. It never heal on its own. If persistent back pain is there then it needs screw fixation. Spondylolisthesis means slippage of vertebral body. It usually causes significant back pain and leg pain. It usually needs surgical management with screw fixation. Minimally Invasive Spine Surgery can treat this problem effectively through small holes.